Published: 2019-06-24

A donor hemovigilance study: evaluation of adverse reactions to blood donors at tertiary care teaching hospital

Sheetal M. Savaliya, Anil P. Singh, Kiran G. Piparva


Background: Donor hemovigilance is an important aspect of the hemovigilance system and contributes to decrease the blood donor’s complications and improving blood donor safety and functioning of blood bank. Reporting of adverse reactions associated with blood donations has been covered under National blood donor vigilance programme. This study was carried out to estimate the adverse events in blood donors and to promote their safety.

Methods: The study was conducted over a period of 6 months, from 1st January 2017 to 30th June 2017 after getting approval from institutional ethics committee at tertiary care teaching hospital. Prior informed consent was obtained and donor confidentiality was ensured. The donors were observed for adverse event during or after donation. For delayed reactions, donors were requested to contact the researcher or designated departmental staff. Data was collected in case record form. Data entry was done in excel 2013 and appropriate Statistical test (chi square) was applied.

Results: During study period total 7970 donors were registered, out of which 53.27% donors have donated their blood in blood camps and 46.72% have in blood bank. Incidence of donor reactions was 1.54%. Incidence of adverse reaction was higher at blood camps (58.53%). Authors found highest number of cases of mild vaso vagal type reactions (53%). Other types of reactions observed were painful arm, hematoma, delayed bleeding, tingling and moderate type of vaso vagal reaction.

Conclusions: Authors did not find any major serious events like convulsion, thrombophlebitis or arterial puncture during study period. It considers that safety of donors was maintained.


Donor hemovigilance, Donor reactions, Donors safety.

Full Text:



Das SC. Donors Hemovigilance: An Institutional Study. Int J Sci Res. 2016;6(5):203-6.

Bisht A, Singh S, Marwaha N. National blood donor vigilance programme India. Asian J Transfus Sci. 2016;10(1):1-2.

Agnihotri N, Marwaha N, Sharma R. Analysis of adverse events and predisposing factors in voluntary and replacement whole blood donors. A study from North India: Asian J Transfus Sci. 2012;6(2):155-60.

Harkin R, Lessig M. Reaction incidence among teen-aged first time and repeat whole blood and apheresis donors. Transfusion. 2007;47(3):105A.

Eder AF, Dy BA, Kennedy JM, Notari IV EP, Strupp A, Wissel ME, et al. The American Red Cross Donor Hemovigilance program, complications of donation reported in 2006. Transfusion. 2008;48(9):1809-19.

Caffrey EA, Butler M, Bissell L, Bowden M, Fry R. Establishing a national adverse event reporting system for blood donors- a prospective study of 1.8 million attendances in England and North Wales. Vox Sang. 2005;1:109-14.

Newman BH. Blood donor complications after whole blood donation. Curr Opin Hematol. 2004;11(5):339-45.

Newman BH. Vasovagal reactions and body weight: findings in high and low risk populations. Transfusion. 2003;43(8):1084-88.

Horowitz SH. Venipuncture-induced nerve injury: a review. J Neuropathic Pain Symptom Palliation. 2005;1(1):109-14.

Newman BH, Waxman DA. Blood donation-related neurologic needle injury. Evaluation of 2 years’ worth of data from a large blood center. Transfusion. 1996;36(3):213-5.

Abhishekh B, Mayadevi S, Usha KC. Adverse reactions to blood donation. Innovative J Med Health Sci. 2013;3(4):158-60.