Published: 2020-05-21

Study and management of type-2 diabetes mellitus in patients with hypertension at tertiary care hospital

B. V. Nagarjuna Yadav, Shaik Tasleem, Shaik Zaheer Basha, Vanipenta Vinay Kumar, Vedururu Sai Harsha Vardhini


Background: This study was aimed to study and management of hypertension in diabetic patients.

Methods: A prospective, observational study was conducted in 160 diabetic hypertensive patients admitted in general medicine wards at Andhra Pradesh Vaidya Vidhana Parishad Hospital, (APVVP), Proddatur. Patients who signed informed consent form were only included in the study. All the data were recorded from patients’ case files and analyzed.

Results: Of enrolled 160 patients, 86 (53.75%) were female and 74 (46.25%) were male and maximum number of the patients 32.5% were found in the age group of 60-69 years. Out of 160 admitted patients, (51) patients treated with metformin, glibenclamide and atenolol, (18) patients treated with metformin, glimiperide, and amlodipine, (6) patients treated with metformin and amlodipine, (28) patients treated with metformin, glimiperide and atenolol, (19) patients treated with metformin and atenolol, (17) patients treated with metformin, glibenclamide and amlodipine,(9) patients treated with metformin, glibenclamide and losartan, (5) patients treated with metformin and losartan, (7) patients treated with metformin, glimiperide, and losartan.

Conclusions: There was less awareness among the patients regarding the control of type-2 diabetes mellitus with hypertension. Majority of diabetic patients noticed with hypertension and β adrenergic blockers remained first choice of drug for hypertension in diabetes. Calcium channel blockers were also prescribed to many patients and were successful to achieve target blood pressure. Among anti-diabetic drugs, biguanides were most frequently prescribed class of drugs. Metformin was the most prescribed drug and Sulphonyl urea were the next most prescribed class of drug.


Hypertension, Diabetes mellitus, Biguanides, β-adrenergic blockers, Calcium channel blockers

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Yohanes A, Kibkab M, Boressa AH. Assesment of drug related problems among type-2 diabetes mellitus patients with hypertension. BMC Res Notes. 2018;11(1):728.

Shruti VB, Bhagya MS. Study on management of hypertension in patients with type-2 diabetes mellitus in tertiary care hospital. Maturitas. 2018;7:2196-8.

Vasilis T, Clicerio G, Ferrannini E. Hypertension and diabetes co-prediction and time trajectories. Hypertension. 2018;71(3):422-8.

Ahasana S, Mohammad A. Prevalence of diabetes and hypertension and association with various risk factors. J Family Med Prim Care. 2018;7(6):1527-36.

Vanathi E, Sachidananda M, Sagar MK, Bheemesh NM, Suresh BS. Study of prescribing pattern of antihypertensive drugs in diabetic patients in a tertiary care centre. Int J Basic Clin Pharmacol. 2019;18:1192-3.

Eze U, Oluwakemi O. Evaluation of drug use among diabetic hypertensive patients in a teaching hospital. Int J Drug Development Res. 2010;2:703.

Zakia H, Amtul S, Salahuddin M, Mohammed AR. Patterns of drug therapy among diabetic hypertensive patients with other complications. Int J Pharm Sci. 2014;6(6):270-7.

Arya SN. Hypertension in diabetic patients-emerging trends. Cardiovasc Diagn Ther. 2003;4:96.

Dimitra I, Pavlou, Stavroula AP, Panagiotis A, Michael S, Eleftherios S, et al. Hypertension in patients with type-2 diabetes mellitus: targets and management. Maturitas. 2018;112:71-7.

Hitender K, Megha G, Shakti BD, Amit V, Amandeep S, Mirza AB. To study the preferred antihypertensive drugs in patients suffering from diabetes mellitus at tertiary care hospital. IJBCP. 2016;5:2033.

Sun D, Zhou T, Heianza Y, Qi L. Type-2 diabetes and hypertension: a study on bidirectional causality. Circulation Research. 2019;124:930-7.

Kim MJ, Lim NK, Park HY. Hypertension is an independent risk factor for type-2 diabetes. Hypertens Res. 2015;38:783.

Okonta JM, Nduka SO, Idodo VE. Prescribing pattern of antihypertensive and antidiabetic agents in secondary health care institution. J Pharmaceutical Sci Res. 2013;5:12.

Kumar AS, Ch SR, Priyanka D. Study of management on comorbid conditions in type-2 diabetes mellitus. J Cell Sci Mutation. 2018;2:16.

Grossman E, Messerli FH. Management of Blood Pressure in Patients with Diabetes. AJH. 2011;24:873.

Prasanna D, Laxman M, Bibek D, Kissan G. Assessment of prescription patterns in hypertensive and diabetic patients visiting private tertiary care hospital of dharan municipality. Sunsari Technical College J. 2015;2(1):44-7.

Vikas P, Ubedul H, Aqil M, Sharma M, Akhtar M, Khandelwal R, et al. Evaluation of prescribing patterns in diabetic and hypertensive patients. IJBCP. 2014;3:494.