Published: 2020-02-25

Knowledge, attitude and practices of postgraduates, interns and nurses, on adverse drug reaction reporting in a tertiary care hospital: a comparative study

Mohana S., Narayanasamy S., Asokan B. R., Smita Kar


Background: Pharmacovigilance is multidisciplinary field of the detection, assessment, understanding, and prevention of adverse drug reactions (ADRs). The incidences of ADRs about 95% are undocumented worldwide. However, there is a lack of information on ADR burden in developing countries due to lack of resources, infrastructure, and expertise.

Methods: A cross-sectional questionnaire-based study was conducted on 90 staff nurses 90interns and 90 postgraduates. The validated questionnaire contained items to check knowledge including 7 questions, 9 questions to analyze attitude and 5 for practices. Comparison between knowledge, attitude and practice data obtained from resident doctors and nurses was performed using Chi square test.

Results: A total of 270 healthcare professionals participated in the study. In our study the participants had good knowledge regarding the purpose of monitoring and reporting ADRs etc. The result shows that health care professionals felt reporting of ADRs is a professional obligation and all ADRs should be reported. There was no significant difference in the knowledge and attitude between interns and nurses but few questionnaires show significant variations between post graduate and staff nurse. The practice of ADR reporting was significantly higher in postgraduate compared to nurses.

Conclusions: This study concluded that post graduate, intern and staff nurse had good knowledge and positive attitude towards pharmacovigilance and ADR reporting, but unfortunately the actual practice of ADR reporting is still deficient among staff nurse and intern. This can be improved by adequate training and motivation.


Adverse drug reactions, Health care professionals, Knowledge, Attitude and practice

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