Suspected immune mediated response to COVID-19 vaccine: two individual case reports

Authors

  • Sagar R. Bhimani Department of Pharmacology, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India
  • Sapna D. Gupta Department of Emergency Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India
  • Kamlesh P. Patel Department of Pharmacology, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India
  • Supriya D. Malhotra Department of Pharmacology, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20212385

Keywords:

COVID 19 vaccine, Adverse event, Pancreatitis, Typhilitis, AEFI

Abstract

SARS-CoV-2, the virus that causes coronavirus disease 19 (COVID-19), has spread rapidly around the world. Researchers have been working round the clock to develop effective vaccines, which people started receiving in December 2020. Therefore, careful follow-up and surveillance studies for continued vaccine safety monitoring will be needed to ascertain the potential risks of such adverse events or disease. Here, we present two individual cases of pancreatitis and typhilitis following COVID 19 vaccination. In the first case of a 38 years old male patient developed pancreatitis after 4 days of COVID 19 vaccination and in second case, of a 60 years old female patient developing typhilitis after just one day after vaccination. All possible causes of this occurrence were ruled out. Two main factors suggest a possible link to the vaccine, the chronology of the events and the incongruent immune response to the vaccine component. It is not possible to establish a direct causal relation between vaccination and adverse event following immunization; however, this report can be used to alert practitioners to this possibility of adverse event following immunization after COVID-19 vaccine.

Author Biographies

Sagar R. Bhimani, Department of Pharmacology, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India

Department of Pharmacology,1st year Resident Doctor

Sapna D. Gupta, Department of Emergency Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India

Department of Emergency Medicine,Associate Professor

Kamlesh P. Patel, Department of Pharmacology, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India

Department of Pharmacology,Associate Professor

Supriya D. Malhotra, Department of Pharmacology, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India

Department of Pharmacology,Professor and Head of Department

References

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Published

2021-06-22

How to Cite

Bhimani, S. R., Gupta, S. D., Patel, K. P., & Malhotra, S. D. (2021). Suspected immune mediated response to COVID-19 vaccine: two individual case reports. International Journal of Basic & Clinical Pharmacology, 10(7), 851–854. https://doi.org/10.18203/2319-2003.ijbcp20212385

Issue

Section

Case Reports